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Related Experiment Video

Updated: Jun 2, 2026

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis (NASH) Resolution

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis (NASH) Resolution

Published on: April 16, 2019

Liver function tests and statins.

Philippe J Zamor¹, Mark W Russo

¹Department of Medicine, Center for Liver Diseases and Transplantation, Carolinas Medical Center, Charlotte, North Carolina 28203, USA.

Current Opinion in Cardiology

|April 19, 2011

Summary

This summary is machine-generated.

Statins are safe and potentially beneficial for patients with elevated liver tests, including those with nonalcoholic fatty liver disease (NAFLD). Recent data indicate statins rarely cause serious liver injury and may improve liver health.

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Last Updated: Jun 2, 2026

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis (NASH) Resolution

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis (NASH) Resolution

Published on: April 16, 2019

Area of Science:

Hepatology
Cardiology
Pharmacology

Background:

Metabolic syndrome and nonalcoholic fatty liver disease (NAFLD) are increasing due to obesity.
Patients with metabolic syndrome often require statin therapy.
Elevated liver tests are common in patients with metabolic syndrome.

Purpose of the Study:

To review current data on statin use in patients with elevated liver tests.
To assess the safety and efficacy of statins in liver disease management.

Main Methods:

Review of recent clinical data and studies.
Analysis of statin effects on liver enzymes and disease progression.

Main Results:

Statins are generally well-tolerated in patients with elevated liver tests.
Serious drug-induced liver injury (DILI) from statins is rare.
Statins may offer therapeutic benefits, including improved response to hepatitis C treatment and reduced aminotransferases in some patients.

Conclusions:

Current evidence supports the use of statins in patients with elevated liver tests.
Statins are particularly recommended for patients with NAFLD due to their high cardiovascular risk.
Statins may have a beneficial role in managing underlying liver conditions.