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Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015
[Short-term effectiveness of arthroscopic anterior cruciate ligament reconstruction with RetroButton-allogeneic
Jingqing Chen1, Baicheng Chen, Shijun Gao
1The Orthopedic Department of Joint Diseases, the Third Hospital of Hebei Medical University, Shijiazhuang Hebei, 050051, P.R.China.
Objective:
To investigate the method and short-term effectiveness of arthroscopic reconstruction of anterior cruciate ligament (ACL) using RetroButton-allogeneic tendon-interference screw.
Methods:
Between June 2009 and October 2009, 23 patients with ACL rupture were treated by arthroscopic reconstruction with RetroButton-allogeneic tendon-interference screw. There were 15 males and 8 females with an average age of 32.5 years (range, 19-46 years), including 17 left knees and 6 right knees. The injury causes were sport trauma (13 cases), traffic accident (8 cases), and falling injury (2 cases). There were 7 acute cases (< 6 weeks) and 16 chronic cases (> 6 weeks). Among the cases, 11 cases complicated by medial meniscus injury, 6 by lateral meniscus injury, 3 by the both injuries, and 5 by articular cartilage injury. All cases had no injuries of posterior cruciate ligament, medial or lateral collateral ligament, or posterolateral structure. The time from injury to operation ranged from 3 weeks to 32 months. Lysholm and International Knee Documentation Committee (IKDC) scores were used for subjective evaluation, while Lachman test and KT-1000 measurement for objective evaluation.
Results:
All wounds healed by first intention. The symptoms of unstable knee were improved obviously. No high fever, infection, or immunologic rejection were observed. Refractoriness synovitis and joint effusion occurred in 1 case after operation, and was improved after articular cavity flushing for 7 times within 3 weeks. All cases were followed up 10-17 months (mean, 14.7 months). There were significant differences in Lysholm score, IKDC score, Lachman test, and KT-1000 measurement between pre-operation and last follow-up (P < 0.05).
Conclusion:
Arthroscopic reconstruction of ACL with RetroButton-allogeneic tendon-interference screw is simple and safe, and its short-term effectiveness is satisfactory.