Related Experiment Video
Updated: Jun 2, 2026

Network Pharmacology Prediction and Experimental Validation of Trichosanthes-Fritillaria thunbergii Action Mechanism Against Lung Adenocarcinoma
Published on: March 3, 2023
Gusanlungionosides A-D, potential tyrosinase inhibitors from Arcangelisia gusanlung
Ling-Ling Yu1, Wei-Cheng Hu, Gang Ding
1Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, People's Republic of China.
Abstract:
Four new megastigmane glycosides, named gusanlungionosides A-D (1-4), together with 10 known compounds (5-14), were isolated from the stems of Arcangelisia gusanlung. The structures and absolute configurations of 1-4 were elucidated by comprehensive analysis of their NMR and CD data. Compounds 1-4 exhibited strong inhibitory effects not only on the mushroom tyrosinase activity in vitro but also on melanogenesis in cells.
Related Concept Videos
Antiprotozoal Agents
Transducer Mechanism: Enzyme-Linked Receptors
Major types that are helpful drug targets include: