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Updated: Jun 2, 2026

Using Mouse Oocytes to Assess Human Gene Function During Meiosis I
Published on: April 10, 2018
Bioinformatics approaches in the discovery and understanding of reproduction-related biomarkers
Athanasios K Anagnostopoulos1, Georgia Tsiliki, George Spyrou
1Proteomics Research Unit, Biomedical Research Foundation of the Academy of Athens, 4 Soranou Ephessiou, 115 27 Athens, Greece.
Abstract:
The emerging field of bioinformatics in proteomics is introducing new algorithms in order to handle large and heterogeneous datasets and improve the knowledge-discovery process. Management systems, software construction and application, database population and leverage, as well as computed prediction, have crafted bioinformatics into a valuable tool for basic research. Human reproduction is one of many fields proteomics has been extensively studying over the last decade, accumulating complex experimental data at a rate far exceeding the ability to assimilate them. Transformation of the rapidly proliferating quantities of experimental information into a usable form in order to facilitate their analysis is a challenging task. On this track, bioinformatics, an essential part of proteomics research, aspires to amend inquiries into a better manipulated, a better handled and a better understood form so as to enhance existing knowledge expansion.
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