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Updated: Jun 2, 2026
Non-Invasive Compression-Induced Anterior Cruciate Ligament (ACL) Injury and In Vivo Imaging of Protease Activity in Mice
Published on: September 29, 2023
[Evaluation of anterior knee laxity on MRI]
M Tardieu1, J-F Luciani, B Bordet
1Service de radiologie, centre hospitalier Lyon-Sud, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France. maxtar2@gmail.com
Purpose:
Evaluation of the ACL and anterior knee laxity on MR during anterior tibial translation.
Patients And Methods:
Three groups were identified based on clinical and arthrometric (KT-1000) data: normal ACL (n=12), complete tear (n=10) and partial tear (n=20). MRI was performed without and with anterior tibial translation (pneumatic device) with morphological and laximetric analysis: drawer tests and dynamic evaluation of ligamentous tension.
Results:
Intra- and inter-observer reproducibility was excellent, correlated to arthrometric data and clinical tests (Lachman, pivot shift). The difference between the drawer signs of normal subjects and patients with ACL tear was significant for a threshold value of 1,1mm for the anterior drawer (sensitivity: 93.33%, specificity: 91.7%) and 2.8 mm for the posterior drawer (sensitivity: 86.7%, specificity: 100%). Dynamic evaluation of ligamentous tension was also reproducible, statistically correlated to the MR drawer tests and reliable for the diagnosis of ACL lesions. In this preliminary study, the distinction between complete and partial ACL tears could not be detected.
Conclusion:
Anterior cruciate ligament function can be demonstrated on MR. The predictive value of this morphological and functional association should be determined in the management of patients with partial tears.