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Histopathological changes in paravertebral muscles by chronic discopathies
O Rozhold1, M Andrs, K Vojácek
1Research Institute of Higher Nervous Activity, Palacký University, Olomouc, Czechoslovakia.
Acta Universitatis Palackianae Olomucensis Facultatis Medicae
|January 1, 1990
Summary
Paravertebral muscle samples from patients with recurrent lumboischiadic syndrome revealed significant histopathological changes. These complex alterations suggest a multifactorial etiology, involving both discogenic factors and primary muscle diseases.
Area of Science:
- Orthopedics
- Neurology
- Pathology
Background:
- Recurrent lumboischiadic syndrome often involves paravertebral muscles.
- Discogenic etiology is a common cause of such syndromes.
- Understanding muscle pathology is crucial for treatment.
Purpose of the Study:
- To investigate the histopathological changes in paravertebral muscles of patients with recurrent lumboischiadic syndrome.
- To explore the relationship between muscle pathology and discogenic etiology.
- To identify potential contributing factors to the observed muscle alterations.
Main Methods:
- Histopathological examination of paravertebral muscle samples from 40 patients.
- Analysis of various grades of pathological alterations.
- Microscopic evaluation of muscle fibers, connective tissue, and neuromuscular spindles.
Main Results:
- All muscle specimens showed pathological alterations, including nonspecific and neurogenic atrophy.
- Myopathic changes such as rounded fibers and nuclear centralization were observed.
- Neuromuscular spindles exhibited thickened capsules and atrophied fibers.
Conclusions:
- Histopathological changes are multifactorial, with a cyclic nature making cause and effect difficult to determine.
- Factors include microtraumas from paravertebral contractures and discopathies.
- Primary muscle diseases and rheumatological conditions may also contribute to spinal degeneration.