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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Computerized decision support systems: improving patient safety in nephrology.

Jamison Chang¹, Claudio Ronco, Mitchell H Rosner

¹Division of Nephrology, University of Virginia Health System, Box 80013, 1215 Lee Street, Charlottesville, VA 22908, USA.

Nature Reviews. Nephrology

|April 20, 2011

Summary

Incorrect medication dosing causes medical errors and adverse drug events (ADEs), especially in patients with kidney disease. Implementing computerized physician order entry and clinical decision support systems can reduce ADEs and improve patient safety.

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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

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TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

Published on: April 13, 2021

Area of Science:

Pharmacology
Nephrology
Health Informatics

Background:

Adverse drug events (ADEs) are a significant cause of medical errors, morbidity, and healthcare costs in the USA.
Patients with chronic kidney disease (CKD) or acute kidney injury (AKI) are at higher risk for ADEs due to impaired drug clearance and polypharmacy.
Physician recognition of CKD/AKI and appropriate drug dosing are often inadequate.

Purpose of the Study:

To highlight the risks of ADEs in patients with kidney impairment.
To emphasize the potential of early interventions and health informatics systems in preventing ADEs.
To advocate for wider implementation of these technologies.

Main Methods:

Review of existing studies on medical errors, ADEs, and kidney disease.
Analysis of the impact of computerized physician order entry (CPOE) and clinical decision support systems (CDSS) on ADE rates.
Discussion of opportunities presented by economic stimulus and healthcare reform.

Main Results:

Inadequate recognition of kidney conditions and incorrect drug dosing contribute to ADEs.
Early interventions and health informatics systems like CPOE and CDSS have demonstrated effectiveness in reducing ADEs.
Current implementation rates of these beneficial systems are surprisingly low.

Conclusions:

There is a critical need to improve drug dosing accuracy in patients with impaired kidney function.
Computerized systems offer a viable solution to mitigate ADEs, but require broader adoption.
Leveraging current healthcare reform presents a unique opportunity to enhance and implement these technologies to reduce patient harm.