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[Further development of P. multocida vaccines for swine]
1Institut für bakterielle Tierseuchenforschung Jena-Zwätzen, Akademie der Landwirtschaftswissenschaften.
Berliner Und Munchener Tierarztliche Wochenschrift
|December 1, 1990
Abstract:
149 strains with antigen fractions of both A and D type could be found out of 446 P. multocida field strains of porcine origin. Most of them are producing the dermonecrotizing toxin. These A/D strains proved to be virulent in mice and piglets as well. In mice, the vaccination with one of the most virulent and immunogenic A/D strains, inactivated and A1(OH)3 adsorbed caused an immunity against challenge infections with P. multocida of types A, D and A/D. This effect could be confirmed on SPF piglets.