Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression of Factor IX cDNA Introduced into Human Marrow Stromal Cells by Electroporation.

Hematology (Amsterdam, Netherlands)·2016
Same author

The French Health Care System; What can We Learn?

The Libyan journal of medicine·2011
Same author

Selected Stro-1-enriched bone marrow stromal cells display a major suppressive effect on lymphocyte proliferation.

International journal of laboratory hematology·2009
Same author

Immunomodulatory effect of mesenchymal stromal cells: possible mechanisms.

Regenerative medicine·2008
Same author

Long-term follow-up of high-dose treatment with autologous haematopoietic progenitor cell support in 693 patients with follicular lymphoma: an EBMT registry study.

Leukemia·2007
Same author

Autologous stem cell transplantation for progressive multiple sclerosis: update of the European Group for Blood and Marrow Transplantation autoimmune diseases working party database.

Multiple sclerosis (Houndmills, Basingstoke, England)·2007

Related Experiment Video

Updated: Jun 2, 2026

Isolating Mesangiogenic Progenitor Cells (MPCs) from Human Bone Marrow
09:53

Isolating Mesangiogenic Progenitor Cells (MPCs) from Human Bone Marrow

Published on: July 15, 2016

Human bone marrow-derived mesenchymal stem cells.

A Nasef1, L Fouillard, A El-Taguri

  • 1EA 1638 -Hématologie, Faculté de Médicine Saint-Antoine, Université de Pierre et Marie Curie, Paris VI, 27 Rue de Chaligny, 75012 Paris, France.

The Libyan Journal of Medicine
|April 20, 2011
PubMed
Summary
This summary is machine-generated.

Mesenchymal stem cells (MSCs) show promise in regenerative medicine and transplantation tolerance. Recent studies highlight their effectiveness in treating steroid-resistant graft-versus-host disease, opening new avenues for cellular therapy.

Keywords:
cancergene therapyimmunomodulationmesenchymal stem cellsplasticity

More Related Videos

Isolation of Human Mesenchymal Stem Cells and their Cultivation on the Porous Bone Matrix
09:00

Isolation of Human Mesenchymal Stem Cells and their Cultivation on the Porous Bone Matrix

Published on: February 9, 2015

Related Experiment Videos

Last Updated: Jun 2, 2026

Isolating Mesangiogenic Progenitor Cells (MPCs) from Human Bone Marrow
09:53

Isolating Mesangiogenic Progenitor Cells (MPCs) from Human Bone Marrow

Published on: July 15, 2016

Isolation of Human Mesenchymal Stem Cells and their Cultivation on the Porous Bone Matrix
09:00

Isolation of Human Mesenchymal Stem Cells and their Cultivation on the Porous Bone Matrix

Published on: February 9, 2015

Area of Science:

  • Stem Cell Biology
  • Immunology
  • Regenerative Medicine

Background:

  • Mesenchymal stem cells (MSCs) are gaining significant clinical attention.
  • Their potential in regenerative medicine and inducing tolerance in transplantation is well-documented.
  • Previous research established the feasibility of MSC transplantation.

Purpose of the Study:

  • To review current knowledge on mesenchymal stem cells (MSCs).
  • To explore the potential future clinical applications of MSCs.
  • To highlight recent findings on MSCs in treating graft-versus-host disease.

Main Methods:

  • Literature review of existing studies on MSCs.
  • Analysis of clinical data regarding MSC transplantation.
  • Synthesis of information on MSC mechanisms and therapeutic potential.

Main Results:

  • MSCs are feasible for transplantation, offering new cellular therapy prospects.
  • MSC injection has successfully induced remission in steroid-resistant acute graft-versus-host disease (GVHD).
  • MSCs demonstrate potential in inducing tolerance in allogeneic transplantation.

Conclusions:

  • Mesenchymal stem cells (MSCs) represent a promising therapeutic agent.
  • Further research into MSCs could revolutionize regenerative medicine and transplantation outcomes.
  • Clinical applications of MSCs, especially for GVHD, warrant continued investigation.