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Cavernous sinus apoplexy presenting isolated sixth cranial nerve palsy: case report
Matteo Zoli1, Diego Mazzatenta, Ernesto Pasquini
1Center of Surgery for Pituitary Tumours, Department of Neurosurgery, Bellaria Hospital, Bologna, Italy. matteozeta@libero.it
Pituitary
|April 20, 2011
Summary
Apoplexy of a pituitary adenoma in the cavernous sinus caused isolated cranial nerve VI palsy. Surgical removal led to prompt recovery, highlighting this rare presentation.
Area of Science:
- Neurology
- Endocrinology
- Neurosurgery
Background:
- Pituitary adenomas can rarely present with apoplexy, a sudden hemorrhage or infarction.
- Cavernous sinus involvement by pituitary adenomas is uncommon, and apoplexy within this location is exceedingly rare.
Observation:
- A 59-year-old female presented with sudden onset of isolated cranial nerve VI palsy and severe headache.
- Magnetic resonance imaging (MRI) revealed a pituitary adenoma within the left cavernous sinus.
- Endoscopic endonasal surgery successfully removed the ischemic adenoma from the cavernous sinus.
Findings:
- The patient experienced rapid resolution of neurological symptoms, including the abducens nerve palsy.
- Post-operative MRI confirmed complete tumor removal, with no evidence of pituitary insufficiency.
- Literature review confirmed the rarity of pituitary adenoma apoplexy exclusively within the cavernous sinus.
Implications:
- This case highlights a unique presentation of pituitary adenoma apoplexy, characterized by isolated abducens nerve palsy and lack of endocrine dysfunction.
- The vulnerability of the abducens nerve within the cavernous sinus may explain the isolated palsy.
- Endoscopic endonasal surgery offers an effective treatment for pituitary adenomas located in the cavernous sinus, even in cases of apoplexy.
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