Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Contemporary achievement of guideline recommendations for blood pressure management after stroke in the CONVINCE trial.

European stroke journal·2026
Same author

A scalable high-throughput serolomics platform for profiling serum antibody responses in large-scale population-based cohorts.

Nature protocols·2026
Same author

Spatial Transcriptomic Profiling Reveals Microenvironment-Dependent Immune Signatures in a Lyme Arthritis model.

bioRxiv : the preprint server for biology·2026
Same author

Kidney Function and Mortality in Mexico: Prospective Study of 130,000 Adults.

Kidney medicine·2026
Same author

BodyMAE: A Surface-Area Aware Masked Autoencoder for Body Composition Estimation from 3D Body Scans.

medRxiv : the preprint server for health sciences·2026
Same author

Endoscopy training under the SIMPL lens: insights on resident competency and autonomy.

Surgical endoscopy·2026

Related Experiment Video

Updated: Jun 2, 2026

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure
07:29

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure

Published on: August 14, 2017

Preoperative liver reduction utilizing a novel nutritional supplement.

Fred Brody1, Khashayar Vaziri, Cathy Garey

  • 1Department of Surgery, The George Washington University Medical Center, Washington, DC 20037, USA. fbrody@mfa.gwu.edu

Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
|April 21, 2011
PubMed
Summary

A novel nutritional supplement, Nuvista, combined with a calorie-restricted diet, significantly reduced liver volume by 43.4% in bariatric surgery patients. This intervention aids in improving surgical outcomes and promoting long-term weight management.

More Related Videos

Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection
06:00

Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection

Published on: December 30, 2025

A Mouse Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy Procedure Aided by Microscopy
06:45

A Mouse Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy Procedure Aided by Microscopy

Published on: January 19, 2024

Related Experiment Videos

Last Updated: Jun 2, 2026

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure
07:29

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure

Published on: August 14, 2017

Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection
06:00

Laparoscopic Anatomic S7+S8d Resection Preserving Inferior Right Hepatic Vein and S6 with Right Hepatic Vein Transection

Published on: December 30, 2025

A Mouse Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy Procedure Aided by Microscopy
06:45

A Mouse Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy Procedure Aided by Microscopy

Published on: January 19, 2024

Area of Science:

  • Bariatric Surgery
  • Hepatology
  • Nutritional Science

Background:

  • Hepatomegaly is a common complication in bariatric surgery, often caused by inadequate exposure of the proximal stomach.
  • This condition can complicate surgical procedures and impact patient outcomes.

Purpose of the Study:

  • To evaluate the efficacy of a novel nutritional supplement (Nuvista) in reducing liver volume preoperatively.
  • To assess the impact of a 4-week calorie-restricted diet and supplement regimen on liver size in morbidly obese patients.

Main Methods:

  • A series of morbidly obese patients received Nuvista for 4 weeks prior to bariatric surgery.
  • Preoperative and intraoperative assessments included demographics, blood work, urine ketone analysis, and liver ultrasonography.
  • Data were analyzed using paired t-tests and bivariate analysis, with P<.05 considered significant.

Main Results:

  • The study included 21 patients (4 men, 17 women) with a mean BMI of 44.5±3.9.
  • After 4 weeks, mean liver volume of the left lateral segment decreased significantly from 562.5±291.3 cm³ to 299.9±162.1 cm³ (P<.001).
  • This represents a mean liver reduction of 43.4%±17.2%, without evidence of starvation indicated by urinary ketone levels.

Conclusions:

  • A 4-week preoperative regimen using Nuvista and calorie restriction significantly reduces liver volume by 43.4%.
  • This approach facilitates improved surgical access and incorporates healthy behaviors essential for sustained weight loss post-bariatric surgery.