Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Two-Dimensional Force System01:20

Two-Dimensional Force System

A two-dimensional system in mechanical engineering involves the analysis of motion and forces in a plane. A two-dimensional force vector can be resolved into its components as:
Three-Dimensional Force System01:30

Three-Dimensional Force System

In mechanical engineering, a three-dimensional force system is a system of forces acting in three dimensions, with forces applied along the x, y, and z coordinate axes. The three-dimensional force system is an important concept in mechanical engineering, as it allows engineers to understand and analyze the behavior of objects and structures in three dimensions. By understanding the forces acting on a system, engineers can design more efficient and effective mechanical systems that can withstand...
Two-Dimensional Force System: Problem Solving01:29

Two-Dimensional Force System: Problem Solving

Solving problems related to two-dimensional force systems is an essential aspect of mechanics and engineering. By applying the principles of vector analysis and force equilibrium, one can determine the effect of multiple forces acting on an object in a two-dimensional space.
The first step to solving a two-dimensional force system problem is to draw a free-body diagram of the object under consideration. This diagram helps identify all the external forces acting on the object, including their...
Three-Dimensional Force System:Problem Solving01:30

Three-Dimensional Force System:Problem Solving

A three-dimensional force system refers to a scenario in which three forces act simultaneously in three different directions. This type of problem is commonly encountered in physics and engineering, where it is necessary to calculate the resultant force on the system, which can then be used to predict or analyze the behavior of the object or structure under consideration.
To solve a three-dimensional force system, first resolve each force into its respective scalar components. Do this using...
Molecular Models02:00

Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
Introduction to force01:25

Introduction to force

Consider water flowing from a nozzle to a turbine vane. As the water hits the turbine vane, it exerts a force that causes it to move along the flow of direction. Force is an impact that changes an object's motion, shape, or orientation. Forces can be caused by physical contact, such as a push or pull, or through non-contact interactions, such as magnetic or gravitational forces. Force is a vector quantity with both magnitude and direction, and is measured in newtons (N) in the SI unit system.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Proteomic profiling of whole tissue sections in cardiac ATTR amyloidosis reveals increased extracellular matrix remodeling.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2026
Same author

Integrated omics reveal a unique antibacterial mechanism of action for the small molecule HSI#6.

Current research in microbial sciences·2026
Same author

Complications of PI to PIII hemipelvic resections for intermediate and malignant tumours : a systematic review and meta-analysis.

Bone & joint open·2026
Same author

Confirmation of monotypic immunofluorescence staining by mass spectrometry in a case of proliferative glomerulonephritis.

Histopathology·2026
Same author

FoldDelay web server: an online tool to quantify translation-driven delays in protein native contact formation.

Nucleic acids research·2026
Same author

Belgian recommendations for tissue diagnosis of amyloidosis.

Acta clinica Belgica·2026
Same journal

Biomedical Concept Recognition with Error-aware Negative-enhanced Ranking Framework.

Bioinformatics (Oxford, England)·2026
Same journal

TEDLH: Domain HMMs for sensitive detection of remote homologues.

Bioinformatics (Oxford, England)·2026
Same journal

PLNFGL: Joint Estimation of Multi-Condition Gene Networks from Single-cell RNA-seq Data.

Bioinformatics (Oxford, England)·2026
Same journal

MCFST: Spatial domain identification method based on multi-view graph convolutional network and graph fusion network.

Bioinformatics (Oxford, England)·2026
Same journal

SpaBiT: Enhancing Spatial Transcriptomics Resolution via Bidirectional Attention Transformers.

Bioinformatics (Oxford, England)·2026
Same journal

EDEL: Enhancing Dense Retrievers for Curation of Biomedical Knowledge Bases.

Bioinformatics (Oxford, England)·2026
See all related articles

Related Experiment Video

Updated: Jun 2, 2026

Modeling an Enzyme Active Site using Molecular Visualization Freeware
14:37

Modeling an Enzyme Active Site using Molecular Visualization Freeware

Published on: December 25, 2021

A graphical interface for the FoldX forcefield.

Joost Van Durme1, Javier Delgado, Francois Stricher

  • 1VIB Switch Laboratory, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

Bioinformatics (Oxford, England)
|April 21, 2011
PubMed
Summary
This summary is machine-generated.

A new graphical user interface (GUI) for the FoldX protein design program has been developed. This plugin for YASARA molecular graphics allows users to easily run protein design calculations and visualize results.

More Related Videos

EasyFiji: A Graphical Interface for User-Friendly Fluorescence Image Processing in Fiji
10:09

EasyFiji: A Graphical Interface for User-Friendly Fluorescence Image Processing in Fiji

Published on: February 20, 2026

Related Experiment Videos

Last Updated: Jun 2, 2026

Modeling an Enzyme Active Site using Molecular Visualization Freeware
14:37

Modeling an Enzyme Active Site using Molecular Visualization Freeware

Published on: December 25, 2021

EasyFiji: A Graphical Interface for User-Friendly Fluorescence Image Processing in Fiji
10:09

EasyFiji: A Graphical Interface for User-Friendly Fluorescence Image Processing in Fiji

Published on: February 20, 2026

Area of Science:

  • Computational biology
  • Protein design
  • Molecular modeling

Background:

  • The FoldX program is a powerful tool for protein design and stability analysis.
  • Existing methods for using FoldX can be complex and require command-line expertise.
  • There is a need for more accessible tools to facilitate protein design workflows.

Purpose of the Study:

  • To develop a user-friendly graphical interface for the FoldX protein design program.
  • To integrate FoldX functionality into the YASARA molecular graphics suite.
  • To simplify complex protein design calculations for researchers.

Main Methods:

  • Developed a plugin for the YASARA molecular graphics suite using Python.
  • Implemented prominent FoldX commands within a windowed menu system.
  • Ensured immediate on-screen visualization of calculation results.

Main Results:

  • A functional graphical user interface (GUI) for FoldX has been successfully created.
  • Users can now execute FoldX commands, including free energy difference upon mutagenesis and interaction energy calculations, through an intuitive menu.
  • Results are displayed directly on screen, enhancing usability.

Conclusions:

  • The developed YASARA plugin provides an accessible and efficient interface for the FoldX protein design program.
  • This tool lowers the barrier to entry for utilizing advanced protein design and analysis techniques.
  • The plugin is freely available for Linux, MacOSX, and MS Windows.