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Pathologic crossroads: cardio-vascular diseases, periodontal diseases and calcium antagonists

H Balan1, E Popescu, G Angelescu

  • 1Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. drhoriabalan@yahoo.com

Journal of Medicine and Life
|April 21, 2011
PubMed

Insights

Chronic inflammation links periodontal diseases (PD) and cardiovascular diseases (CVD). Further research is needed to confirm a causal relationship between these prevalent conditions.

Area of Science:

  • Periodontology and Cardiology
  • Chronic Inflammation Research

Background:

  • Chronic inflammation is increasingly recognized as a key factor in cardiovascular diseases (CVD), particularly in the development and progression of atherosclerosis.
  • Periodontal diseases (PD) are highly prevalent chronic inflammatory conditions affecting a large portion of the population.

Purpose of the Study:

  • To investigate the potential causal relationship between periodontal diseases (PD) and cardiovascular diseases (CVD).
  • To explore the scientific and clinical significance of establishing a link between these two widespread pathologies, given that PD is preventable and treatable.

Main Methods:

  • A comprehensive review of existing data on the relationship between PD and CVD.

Main Results:

  • The review synthesizes current evidence regarding the association between periodontal diseases and cardiovascular diseases.
  • Shared risk factors contribute to the prevalence of both conditions.

Conclusions:

  • Establishing a definitive causal link between PD and CVD is complex.
  • The widespread use of calcium antagonists (CA) for CVD treatment may complicate the investigation of this relationship.
Abstract

Keywords:
atherosclerosiscalcium antagonistscardiovascular diseasesgingival overgrowthperiodontal diseases

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