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Related Concept Videos

Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as a...
Bipolar Disorder01:30

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
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Antianxiety Medications
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Dosage Regimen: Individualization01:24

Dosage Regimen: Individualization

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Antidepressant Drugs: MAOIs and Other Agents

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Related Experiment Videos

Customization in prescribing for bipolar disorder.

Dominic Hodgkin1, Joanna Volpe-Vartanian, Elizabeth L Merrick

  • 1Institute for Behavioral Health, Heller School of Social Policy & Management, Brandeis University, Waltham, MA 02454, USA. hodgkin@brandeis.edu

Health Economics
|April 21, 2011
PubMed
Summary

Physician treatment customization for bipolar disorder is limited, with patient clinical status playing a small role. Prescribing patterns varied significantly between doctors, not based on patient needs.

Related Experiment Videos

Area of Science:

  • Psychiatry
  • Clinical Pharmacology
  • Health Services Research

Background:

  • Patient heterogeneity necessitates tailored treatments for complex conditions like bipolar disorder.
  • Physician prescribing practices are a key factor in bipolar disorder management.
  • The degree of treatment customization in real-world clinical settings remains under-investigated.

Purpose of the Study:

  • To evaluate the extent of physician customization in prescribing drug combinations for bipolar disorder.
  • To determine if patient clinical status influences physician treatment choices.
  • To assess variability in prescribing patterns across different physicians.

Main Methods:

  • Utilized data from the naturalistic clinical effectiveness trial of bipolar disorder treatment (STEP-BD).
  • Employed multinomial logit modeling to analyze physician choices among five drug class combinations.
  • Focused on patient clinical status as a predictor of prescribing decisions.

Main Results:

  • Patient clinical status had a limited impact on the selection of drug class combinations.
  • Significant variation in treatment choices was observed among different physicians for patients with similar characteristics.
  • The predictive power of the model for prescribing choices was low.

Conclusions:

  • Physician prescribing for bipolar disorder shows limited evidence of customization based on patient clinical status.
  • Inter-physician variability in treatment selection is substantial.
  • Further research is needed to understand factors driving prescribing decisions in bipolar disorder management.