Related Experiment Video
Updated: Jun 2, 2026

Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation
Published on: March 4, 2016
[Autodermoplasty with split skin grafts in treatment of pyoderma gangrenosum]
Abstract:
Pyoderma gangrenosum (PG) is a rare infectious disease which usually shows itself as painful ulcers on the lower leg. At the present time the autoimmune nature of the disease seems to be most probable. PG is characterized by a phenomenon of pathergy--actuation of the inflammatory process and appearance of ulcers in traumas of the skin. So autodermoplasty of the ulcers in case of PG was "under a ban". In the recent time there appeared publications justifying using methods under conditions of systemic immunosuppressive therapy. Unfortunately the latter is often associated with a great number of side effects which sometimes can result in death.
Related Concept Videos
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Clinical Applications of Epidermal Stem Cells

