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Vitamin D deficiency among healthy infants and toddlers: a prospective study from Irbid, Jordan
Khalid K Abdul-Razzak1, Mohammed-Jafar A Ajlony, Abeer M Khoursheed
1Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan. kkalani@just.edu.jo
Insights
Vitamin D deficiency is common in Jordanian infants and toddlers, with low sun exposure and exclusive breastfeeding being major risk factors. These findings highlight the need for targeted interventions to improve vitamin D levels in this population.
Area of Science:
- Pediatrics
- Nutritional Science
- Public Health
Background:
- Vitamin D deficiency is a growing concern in pediatric populations globally.
- Assessing prevalence and risk factors is crucial for public health initiatives.
Purpose of the Study:
- To determine the prevalence of vitamin D deficiency and insufficiency in healthy infants and toddlers (6-36 months) in Irbid, Jordan.
- To identify associated factors, including sociodemographic characteristics and feeding practices.
Main Methods:
- A cross-sectional study involving 275 infants and toddlers.
- Data collection via questionnaires on sociodemographics and feeding patterns.
- Biochemical analysis of plasma vitamin D, calcium, phosphorous, and alkaline phosphatase.
Main Results:
- The prevalence of vitamin D deficiency was 28% (severe: 16.7%, deficiency: 11.3%), and insufficiency was 28.4%.
- Significant associations were found between vitamin D status and sun exposure (P < 0.001) and infant feeding practices (P < 0.001).
- Exclusive breastfeeding was linked to a higher risk of deficiency and insufficiency. Female sex, low sun exposure, and exclusive breastfeeding were key determinants.
Conclusions:
- Vitamin D deficiency is highly prevalent among infants and toddlers in northern Jordan.
- Inadequate sun exposure (<30 min daily) and exclusive breastfeeding are primary contributors to vitamin D deficiency.
Background:
The aim of this study was to estimate the prevalence of vitamin D deficiency among healthy infants and toddlers, as well as its associated factors, in Irbid, Jordan.
Methods:
A total of 275 subjects (136 infants and 139 toddlers) aged 6-36 months participated in this study. Information concerning sociodemographic characteristics and early feeding patterns was collected using a self-guided questionnaire. Plasma vitamin D, calcium, phosphorous, and alkaline phosphatase activity were measured.
Results:
The prevalence of vitamin D deficiency was 28% (16.7% for severe vitamin D deficiency and 11.3% for vitamin D deficiency) and vitamin D insufficiency was 28.4%. Plasma calcium and alkaline phosphatase levels showed no correlation with the vitamin D status of the study population. For both age groups, a significant association was found between vitamin D status and sun exposure (P < 0.001). A significant association between infant feeding practices and vitamin D status was found (P < 0.001). Infants who were exclusively breast-fed had higher risk for vitamin D deficiency and vitamin D insufficiency than those who were bottle-fed. Multivariate logistic regression analyses results showed that female sex, low sun exposure and exclusive breast-feeding were the main determinants of vitamin D levels.
Conclusion:
The prevalence of vitamin D deficiency is considered to be high among northern Jordanian infants and toddlers. Sun exposure of less than 30 min daily and exclusively breast-feeding are the main factors for developing vitamin D deficiency.
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