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Published on: November 15, 2019
[Reversible optic neuropathy related to disulfiram]
1Service d'ophtalmologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 09, France. lecq_anne@yahoo.fr
Objective:
To report a case of bilateral optic neuropathy, possibly caused by disulfiram.
Patients And Methods:
Clinical case report.
Results:
A 46-year-old patient, treated with disulfiram for the past 4 years for chronic alcoholism, presented with progressive bilateral, painless, severe visual loss, related to optic neuropathy. An extensive work-up did not disclose any other possible cause than a toxic optic neuropathy caused by disulfiram. Discontinuation of disulfiram resulted in rapid, complete visual recovery.
Conclusion:
Disulfiram can cause toxic optic neuropathy, which can recover after discontinuing the medication, even after a long period of intoxication.
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