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Updated: Jun 2, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Glaucoma and sleep apnea syndrome].
E Blumen-Ohana1, M Blumen, F Aptel
1Centre hospitalier des Quinze-Vingts, 28, rue de Charenton, 75012 Paris, France. blumen-ohana@club-internet.fr
Glaucomatous optic neuropathy can progress despite controlled eye pressure. Obstructive sleep apnea syndrome (OSAS) is a potential vascular risk factor that warrants screening in affected patients.
Area of Science:
- Ophthalmology
- Neurology
- Cardiology
Background:
- Glaucomatous optic neuropathy is a leading cause of irreversible blindness.
- Intraocular pressure (IOP) is the primary modifiable risk factor, but some patients progress despite controlled IOP.
Observation:
- Progression of glaucomatous optic neuropathy may occur even with seemingly controlled IOP.
- Vascular risk factors are increasingly investigated as contributing factors.
Findings:
- Obstructive sleep apnea syndrome (OSAS) is a potential vascular risk factor implicated in glaucomatous optic neuropathy.
- Screening for OSAS in glaucoma patients with suggestive signs is proposed.
Implications:
- Identifying and managing OSAS could offer a new therapeutic target for glaucoma.
- This may improve the long-term prognosis for patients with glaucoma and uncontrolled progression.
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