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Cogan's syndrome
1Department of Neurology, University of Bern, Switzerland.
Abstract:
Cogan's syndrome is a rare systemic autoimmune disease with preeminent ophthalmological and vestibulocochlear manifestations. Untreated, the disease usually results in profound deafness; eye involvement is usually self-remitting. Ten to twenty percent of patients either develop serious aortic valve disease or vasculitis or both. When given early, immunosuppressive therapy has been shown to be effective in treating all aspects of the disease. Thus, early disease recognition is of great significance. We present a patient with Cogan's syndrome and briefly discuss therapeutic implications.
Insights
Early recognition of Cogan
Area of Science:
- Rheumatology
- Ophthalmology
- Otolaryngology
Background:
- Cogan's syndrome is a rare systemic autoimmune disorder.
- It primarily affects the eyes and the vestibular system, potentially leading to deafness.
- A subset of patients develop serious cardiovascular complications like aortic valve disease or vasculitis.
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