Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Uterus and Cervix

Uterus and Cervix

The uterus, commonly called the womb, is a vital reproductive organ in females designed to provide a nurturing environment for the implantation and growth of an embryo. It is shaped like a hollow pear and positioned between the urinary bladder and the rectum. The uterus's structure allows it to support and protect a developing fetus throughout pregnancy.
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs of...

Uterine Tubes

Uterine Tubes

The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...

Disorders of the Female Reproductive System

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The stentless temptation: drug-coated balloons between evidence, enthusiasm, and historical caution.

Journal of cardiovascular medicine (Hagerstown, Md.)·2026

Same author

Innovation through standardization: Reducing the ileostomy rates while targeting zero anastomotic leaks at cytoreductive surgery.

Gynecologic oncology·2026

Same author

Dedicated versus non-dedicated transcatheter valves for pure native aortic regurgitation: a single-centre experience.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2026

Same author

Trends and comparative study of robotic-assisted benign hysterectomy among morbidly obese patients in united States.

Journal of robotic surgery·2026

Same author

Whole-transcriptome sequencing and machine learning detect molecular signatures of endometrial cancer in non-invasive vaginal swabs.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2026

Same author

Long-Term Survival in High-Grade Serous Ovarian Cancer Compared With the General US Population: A 30-Year Landmark Analysis.

JCO oncology advances·2026

Search research articles

Related Experiment Video

Updated: Jun 2, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

Uterine carcinosarcoma.

Sherif A El-Nashar¹, Andrea Mariani

¹Division of Gynecologic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Clinical Obstetrics and Gynecology

|April 22, 2011

Summary

This summary is machine-generated.

Carcinosarcoma, a rare uterine cancer, is aggressive and biphasic. Management involves surgical staging and multimodal therapy including radiation and chemotherapy for all stages.

Related Experiment Videos

Last Updated: Jun 2, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

Area of Science:

Gynecologic Oncology
Surgical Pathology
Cancer Therapeutics

Background:

Carcinosarcoma is a rare uterine malignancy characterized by high aggressiveness.
Pathologically, it presents as a biphasic neoplasm with both malignant epithelial and mesenchymal elements.

Purpose of the Study:

To outline the recommended management approach for uterine carcinosarcoma.
To emphasize the importance of a comprehensive strategy for this aggressive cancer.

Main Methods:

Complete surgical staging to evaluate tumor spread.
Multimodal therapy incorporating radiation (external beam or brachytherapy) and chemotherapy.

Main Results:

The study recommends a comprehensive management plan for uterine carcinosarcoma.
This includes surgical staging followed by multimodal therapy for both early and advanced stages.

Conclusions:

Uterine carcinosarcoma requires a multimodal treatment approach.
Complete surgical staging and a combination of radiation and chemotherapy are crucial for effective management.