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Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistent Cancers02:56

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta-Analysis of the European Myeloma Network (EMN).

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An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
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Published on: July 15, 2015

Supportive therapy in multiple myeloma.

Heinz Ludwig1, Niklas Zojer

  • 1Department of Medicine I, Wilhelminenspital, Montleartstr. 37, 1160, Vienna, Austria. heinz.ludwig@wienkav.at

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|April 22, 2011
PubMed
Summary
This summary is machine-generated.

This chapter reviews supportive care strategies for multiple myeloma patients. These measures aim to prevent complications, enhance patient well-being, and ensure safe anti-myeloma treatment.

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Area of Science:

  • Hematology
  • Oncology
  • Supportive Care

Background:

  • Multiple myeloma is a complex hematologic malignancy requiring comprehensive management.
  • Treatment of multiple myeloma can lead to significant complications and impact patient quality of life.

Purpose of the Study:

  • To provide an overview of supportive measures for multiple myeloma patients.
  • To discuss strategies for preventing and managing treatment complications.
  • To highlight methods for improving patient well-being and treatment safety.

Main Methods:

  • Literature review of supportive care in multiple myeloma.
  • Synthesis of evidence-based recommendations for supportive interventions.
  • Discussion of clinical best practices in managing myeloma-related issues.

Main Results:

  • Supportive measures are crucial for optimizing outcomes in multiple myeloma.
  • Key interventions include managing side effects, nutritional support, and psychosocial care.
  • Proactive management enhances patient safety and tolerance to anti-myeloma therapies.

Conclusions:

  • Comprehensive supportive care is integral to the multidisciplinary management of multiple myeloma.
  • Implementing these strategies can significantly improve patient well-being and treatment efficacy.
  • Further research into novel supportive interventions is warranted to address evolving treatment landscapes.