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Related Concept Videos

Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Related Experiment Video

Updated: Jun 2, 2026

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
08:39

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

Published on: November 7, 2020

Long-term outcomes after third liver transplant.

C Burcin Taner1, Deniz Balci, Darrin L Willingham

  • 1Department of Transplantation, Mayo Clinic Florida, Jacksonville, FL 32224, USA. taner.burcin@mayo.edu

Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation
|April 23, 2011
PubMed
Summary

Multiple orthotopic liver transplants can lead to acceptable patient survival, even after third graft failure. Transplant centers should consider program volume and outcomes when deciding on these complex retransplants.

Related Experiment Videos

Last Updated: Jun 2, 2026

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation
08:39

Reduced Complications after Arterial Reconnection in a Rat Model of Orthotopic Liver Transplantation

Published on: November 7, 2020

Area of Science:

  • Hepatology
  • Transplant Surgery
  • Immunology

Background:

  • Orthotopic liver transplant is standard for end-stage liver disease.
  • Liver retransplant after first graft failure is common.
  • Third orthotopic liver transplant is rare and performed at select centers.

Purpose of the Study:

  • To analyze long-term outcomes of patients undergoing three or more orthotopic liver transplants.
  • To evaluate survival rates and influencing factors in this unique patient cohort.

Main Methods:

  • Retrospective analysis of 24 patients who received 3+ orthotopic liver transplants.
  • Data collected from February 1998 to August 2009 at Mayo Clinic, Florida.
  • Examined patient survival and graft donor risk index scores.

Main Results:

  • Mean patient survival was 103.8 months.
  • Actuarial survival at 1, 5, and 10 years post-transplant was 60%, 40%, and 33%, respectively.
  • Lower donor risk index scores correlated with better survival; scores >1.6 significantly reduced survival rates.

Conclusions:

  • Multiple liver retransplants demonstrate acceptable patient survival.
  • Transplant programs must weigh individual program volume and outcomes.
  • Consideration of access for first-time transplant candidates is crucial in decision-making.