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Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
Experience with patients with anti-MUSK antibody positive myasthenia gravis
Uma Sundar1, Preeti Shaunbhag, Yogesh Lakkas
1Internal Medicine and Neurology Services, Lokmanya Tilak Municipal General Hospital and Medical College, Mumbai, India.
Abstract:
The association of muscle tyrosine kinase (Musk) antibody with recurrent bulbar weakness in acetylcholine receptor antibody (Ach-R Ab) negative myasthenia gravis (MG) has been well documented. We describe 2 patients, a middle aged man and a 9-year-old girl, both seronegative for Ach R antibody who had recurrent bulbar weakness and MUSK antibody positivity. Patients made a full recovery from the acute episode with intravenous immunoglobulin (IV Ig) therapy. The peculiar clinical features of this condition and its management are discussed.
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