Characteristics of spherical aberrations in 3 aspheric intraocular lens models measured in a model eye

To evaluate the spherical aberration in aspheric intraocular lenses (IOLs) using a model eye.

Nara Medical University, Nara, Japan.

Experimental study.

This study tested 20.00 diopter (D) and 10.00 to 30.00 D aspheric IOLs in a fluid-filled model constructed to replicate the optical condition of a pseudophakic human eye. Spherical aberration was measured by Hartmann-Shack aberrometry. The 3 IOLs tested were the Acryfold AC60AD (IOL AC), Acrysof IQ SN60WF (IOL IQ), and Tecnis ZA9003 (IOL ZA). The 1-sample t test and Pearson correlation analysis were used for statistical evaluation.

The measured spherical aberration in the 20.00 D IOL AC was statistically significantly less than the manufacturer-indicated value (P=.0020); there was no significant difference for the 20.00 D IOL IQ and IOL ZA. The correlation between IOL power and spherical aberration was significant for IOL AC with a 4.0 mm aperture (P=.0007, r = -0.646) and 6.0 mm aperture (P<.0001, r=-0.684), IOL IQ with a 4.0 mm aperture (P=.040, r=-0.390) but not with a 6.0 mm aperture (P=.929), and IOL ZA with a 4.0 mm aperture (P<.0001, r=-0.696) and 6.0 mm aperture (P=.011, r=-0.470).

Negative correlations were found between IOL power and spherical aberration for 3 aspheric IOL models, particularly for IOL AC and IOL ZA. In a clinical setting, aspheric IOL implantation may result in negative spherical aberration that could exceed the manufacturer-indicated value.