Related Experiment Video
Updated: Jun 2, 2026
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Complications in acute stroke in India (CAST-I): a multicenter study
Jeyaraj D Pandian1, Arshpreet Kaur, Rashmi Jyotsna
1Stroke Unit, Department of Neurology, Christian Medical College, Ludhiana, Punjab, India. jeyarajpandian@hotmail.com
Summary
Acute stroke complications affect patient outcomes. This study found high complication rates in India, with limb weakness, anemia, and stroke severity linked to their occurrence.
Area of Science:
- Neurology
- Public Health
- Internal Medicine
Background:
- Medical complications during acute stroke significantly impact prognosis.
- Limited data exists on acute stroke complications in India and developing nations.
Purpose of the Study:
- To investigate the frequency of acute stroke complications in India.
- To identify factors associated with these complications and their impact on patient outcomes.
Main Methods:
- A prospective, multicenter study involving 6 hospitals in India.
- Collected data on stroke characteristics, complications, and 30-day outcomes in 449 patients.
- Utilized the modified Rankin Scale and National Institutes of Health Stroke Scale for assessment.
Main Results:
- 45.9% of patients experienced acute stroke complications.
- Factors associated with complications included limb weakness, anemia, longer hospital stay, and stroke severity.
- Complications like urinary tract infection, chest infection, bedsores, pain, and depression were linked to poor outcomes.
Conclusions:
- Acute stroke patients in India face high rates of complications.
- Identifying and managing factors like limb weakness, anemia, and stroke severity is crucial.
- Specific complications require targeted interventions to improve patient prognosis.
Related Concept Videos
01:15Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
01:17Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
01:15Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
01:30Acute Coronary Syndrome III: Diagnostic Studies
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
01:29Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...