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Functional glucokinase regulator gene variants have inverse effects on triglyceride and glucose levels, and decrease

K Horvatovich1, S Bokor, N Polgar

  • 1Department of Medical Genetics and Child Development, University of Pecs, Szigeti út 12, 7624 Pécs, Hungary.

Diabetes & Metabolism
|April 23, 2011
PubMed
Summary

Minor alleles of the glucokinase regulatory protein (GCKR) gene variants are linked to lower triglycerides and glucose levels. These GCKR variants offer protection against childhood obesity, suggesting potential benefits against adult diabetes and metabolic syndrome.

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