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Updated: Jun 2, 2026

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery
Published on: November 14, 2018
Nasal obstruction as a drug side effect
Cemal Cingi1, Tunis Ozdoganoglu, Murat Songu
1Department of Otorhinolaryngology, Osmangazi University Medical Faculty, Eskisehir, Turkey.
Abstract:
Nasal obstruction is a common symptom of various diseases, allergies, and structural deformities and a 'stuffy nose' is one of the most common reasons that patients seek a physician's aid. Drugs that affect the autonomic nervous system are also expected to have a vasoactive effect on the nose. Nasal obstruction in the absence of infectious rhinitis or allergic symptoms may be due to drug use. With the chronic use of a medication, nasal obstruction can change over time and can be underestimated. Very little is known about this topic and very few publications to date solely devoted to drug-induced rhinitis. To prevent complications, obvious nasal obstruction due to drug intake should be treated with appropriate medication(s) or surgical intervention(s).
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