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A tentative consensus-based model for priority setting: an example from elderly patients with myocardial infarction
Niklas Ekerstad1, Rurik Löfmark, David Andersson
1The Center for Medical Technology Assessment/IMH, Linköping University, Sandbäcksgatan 7, 58183 Linköping, Sweden. niklas.ekerstad@ihs.liu.se
Insights
A new model for prioritizing care for frail elderly heart patients, considering comorbidity, frailty, and cardiovascular risk, shows high expert agreement. This framework can guide evidence-based guidelines for complex cardiac cases in older adults.
Area of Science:
- Cardiology
- Geriatrics
- Health Services Research
Background:
- Evidence-based guidelines are crucial but challenging with weak evidence bases, particularly for frail elderly patients with heart disease.
- A tentative model integrating cardiovascular risk, frailty, and comorbidity was developed for priority setting in this population.
- Validating this model is essential for its practical application in clinical decision-making.
Purpose of the Study:
- To validate the components of a proposed priority-setting model for frail elderly heart patients.
- To assess the inter-rater reliability of expert rankings for the model's key categories.
Main Methods:
- A confidential questionnaire study involving 58 cardiology experts.
- Experts ranked 15 validated clinical cases based on the need for coronary angiography.
- Inter-rater reliability was analyzed using intra-class correlation (ICC) statistics.
Main Results:
- The model's components demonstrated very good inter-rater reliability (ICC = 0.978) among experts.
- Comorbidity was ranked as the most relevant factor, followed by frailty and cardiovascular risk.
- Experts found the clinical cases realistic and the model relevant for non-ST elevation myocardial infarction cases.
Conclusions:
- A framework incorporating comorbidity, frailty, and cardiovascular risk can form the basis for consensus guidelines for frail elderly cardiac patients.
- The proposed framework is likely applicable to other elderly patient groups with acute conditions and complex needs.
- This approach supports evidence-based priority setting in geriatric cardiology.
Background:
In most Western countries the growing gap between available resources and greater potential for medical treatment has brought evidence-based guidelines into focus. However, such guidelines are difficult to use when the evidence base is weak. Priority setting for frail elderly patients with heart disease illustrates this problem. We have outlined a tentative model for priority setting regarding frail elderly heart patients. The model takes cardiovascular risk, frailty, and comorbidity into account.
Objective:
Our aim is to validate the model's components. We want to evaluate the inter-rater reliability of the study experts' rankings regarding each of the model's categories.
Methods:
A confidential questionnaire study consisting of 15 authentic and validated cases was conducted to assess the views of purposefully selected cardiology experts (n = 58). They were asked to rank the cases regarding the need for coronary angiography using their individual clinical experience. The response rate was 71%. Responses were analysed with frequencies and descriptive statistics. The inter-rater reliability regarding the experts' rankings of the cases was estimated via an intra-class correlation test (ICC).
Results:
The cardiologists considered the clinical cases to be realistic. The intra-class correlation (two-way random, consistency, average measure) was 0.978 (95% CI 0.958-0.991), which denotes a very good inter-rater reliability on the group level. The model's components were considered relevant regarding complex cases of non-ST elevation myocardial infarction. Comorbidity was considered to be the most relevant component, frailty the second most relevant, followed by cardiovascular risk.
Conclusions:
A framework taking comorbidity, frailty, and cardiovascular risk into account could constitute a foundation for consensus-based guidelines for frail elderly heart patients. From a priority setting perspective, it is reasonable to believe that the framework is applicable to other groups of elderly patients with acute disease and complex needs.
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