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Updated: Jun 2, 2026

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
05:32

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

Nuclear medicine in myeloma: the state of the science and emerging trends

Ashwani Sood, Swaroop Revannasiddaiah, Rakesh Kumar

    Hellenic Journal of Nuclear Medicine
    |April 23, 2011
    PubMed

    We present the different imaging modalities in relation to myeloma, ranging from the time tested X-ray radiography to the newer promising methods of fluorine-18 fluorodesoxyglucose-positron emission tomography ((18)F-FDG-PET) and technetium-99m methoxy isobutyl isonitrite ((99m)Tc-MIBI) scintigraphy. A small discussion regarding newer methods such as fluoride-18 positron emission tomography ((18)F-PET), fluorine-18-fluoro-deoxy-L-thymidine positron emission tomography ((18)F-FLT PET), carbon-11 methionine positron emission tomography ((11)C-methionine PET) and the tritiated thymidine labeling index is also included. They have different mechanisms of tracer uptake enabling the visualization of the spectrum of the disease manifestations ranging from osteoblastic to osteolytic lesions, and also the study of the metabolic status, proliferative and protein activity, in skeletal and in extra-skeletal sites.

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