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The ALK gene, an attractive target for inhibitor development

Carmen J Tartari1, Leonardo Scapozza, Carlo Gambacorti-Passerini

  • 1Department of Clinical Medicine, University of Milano-Bicocca, Italy. carlo.gambacorti@unimib.it

Current Topics in Medicinal Chemistry
|April 26, 2011
PubMed
Summary

Anaplastic Lymphoma Kinase (ALK) is crucial in neural development and tumors. Small molecule inhibitors targeting ALK kinase activity are being developed to combat cancers driven by ALK fusion proteins.

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