Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors01:20

Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors

Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hemostatic and platelet proteins are associated with bleeding grade and time to major bleed in hemato-oncological patients.

Blood vessels, thrombosis & hemostasis·2026
Same author

Clinical evaluation of novel blood collection and storage bags containing alternative plasticizers to DEHP: Recommendations from the BEST collaborative.

Transfusion·2025
Same author

Pathogen inactivation of red cell concentrates and whole blood: I. History, technologies and in vitro product preservation studies.

Vox sanguinis·2025
Same author

Pathogen inactivation of red cell concentrates and whole blood: II. In vivo human recovery studies, clinical trials and future directions.

Vox sanguinis·2025
Same author

Impact of platelet transfusions on plasma proteomes in controlled endotoxemia and in hemato-oncological patients.

Transfusion·2025
Same author

Clinical evaluation of red cell concentrates in non-DEHP plasticized containers compared with standard DEHP plasticized containers: A quasi-randomized observational multicentre study.

Vox sanguinis·2025

Related Experiment Video

Updated: Jun 2, 2026

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
12:40

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System

Published on: December 7, 2012

Platelet preservation: agitation and containers.

Pieter F van der Meer1, Dirk de Korte

  • 1Department of Product and Process Development, Sanquin Blood Bank, Amsterdam, The Netherlands. p.vandermeer@sanquin.nl

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|April 26, 2011
PubMed
Summary
This summary is machine-generated.

Gentle agitation and gas-permeable containers are crucial for maintaining platelet quality and effectiveness during storage. Proper storage conditions prevent platelet activation and damage, ensuring optimal in vitro quality and in vivo effectiveness.

More Related Videos

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination
10:32

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination

Published on: August 24, 2015

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets
05:49

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets

Published on: November 29, 2024

Related Experiment Videos

Last Updated: Jun 2, 2026

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
12:40

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System

Published on: December 7, 2012

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination
10:32

Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination

Published on: August 24, 2015

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets
05:49

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets

Published on: November 29, 2024

Area of Science:

  • Transfusion Medicine
  • Biomaterials Science

Background:

  • Platelet storage requires specific conditions to maintain quality and effectiveness.
  • Room temperature storage with gentle agitation in gas-permeable containers is optimal.
  • Previous storage methods led to platelet activation and damage.

Purpose of the Study:

  • To review the impact of storage conditions on platelet quality.
  • To discuss the role of agitation and container materials.
  • To highlight advancements and future research directions in platelet storage.

Main Methods:

  • Review of literature on platelet storage.
  • Analysis of agitation methods (circular, flat bed, tumblers, elliptical).
  • Evaluation of gas-permeable plastics for container manufacturing.

Main Results:

  • Gentle agitation (circular or flat bed) preserves platelet quality.
  • Tumblers or elliptical agitators cause platelet activation and damage.
  • Improved gas-permeability has extended storage from 3 to at least 7 days.
  • Continuous oxygenation and CO2 expulsion are vital during agitation.

Conclusions:

  • Optimal platelet storage involves room temperature, gentle agitation, and gas-permeable containers.
  • Agitation speed is less critical than the mode of agitation.
  • Extended storage is possible due to advancements in container technology.
  • New developments necessitate further research into platelet storage optimization.