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Oral agents in cancer treatment: the context for adherence
1Oncology, Mayo Clinic, 200 First Street SW, Charlton 6-133, Rochester, MN 55905, USA. barton.debra@mayo.edu
Objectives:
To review oral agents approved for cancer, discuss their mechanism of action and/or molecular targets, and outline side effects and challenges that impact adherence.
Data Sources:
Peer reviewed literature and on-line drug information.
Conclusion:
Oral agents to treat cancer, although not new, are common and increasing dramatically. The context of adherence to oral agents is complicated by increased knowledge of food-drug interactions and combinations of agents with overlapping or synergistic toxicity profiles.
Implications For Nursing Practice:
The role of nursing in the administration and education of oral cancer treatments is critical to optimal treatment outcomes.
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