Related Experiment Video
Updated: Jun 2, 2026

Single-Molecule Localization Microscopy of Membrane Proteins using Single-Antibody Labeling
Published on: March 20, 2026
Homing-associated molecules CD73 and VAP-1 as targets to prevent harmful inflammations and cancer spread
1MediCity Research Laboratory, University of Turku and National Institute of Health and Welfare, Turku, Finland.
Abstract:
Homing-associated molecules are of fundamental importance for proper functioning of our immune system as they direct the cells to sites of inflammation to create an immune response. However, they are also responsible for harmful cell trafficking, which takes place in acute and chronic inflammations as well as in tumor progression and metastatic spread of cancer. Therefore, these molecules are potential targets for developing drugs to prevent harmful inflammation and metastases of cancer. In this review, we will discuss about the most recent advances in studies elucidating the role of two homing-associated ecto-enzymes in physiological and pathological cell trafficking and their use as drug targets.
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