Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Role of cellular casein kinase II in the function of the phosphoprotein (P) subunit of RNA polymerase of vesicular stomatitis virus.

The Journal of biological chemistry·1995
Same author

Case of the month: a painful red eye.

The British journal of radiology·1995
Same author

Double reading of magnetic resonance imaging films.

The National medical journal of India·1995
Same author

Local excision of rectal tumours.

The British journal of surgery·1995
Same author

Human parainfluenza virus type 3 phosphoprotein: identification of serine 333 as the major site for PKC zeta phosphorylation.

Virology·1995
Same author

An audit of fatal acute pancreatitis.

Postgraduate medical journal·1995
Same journal

Switching to long-acting anti-retroviral therapy with no baseline resistance data: is there value in proviral DNA sequencing? A single-centre pilot study.

International journal of STD & AIDS·2026
Same journal

A precautionary tale of lenacapavir drug-drug interactions: A case series of two persons living with HIV receiving long-acting injections.

International journal of STD & AIDS·2026
Same journal

Long-acting injectable cabotegravir/rilpivirine in a pregnant woman living with HIV with hyperemesis gravidarum:a case report and review of literature.

International journal of STD & AIDS·2026
Same journal

BASHH best practice statement on the management of testosterone-associated vulvovaginitis.

International journal of STD & AIDS·2026
Same journal

Diagnostic accuracy of the Xpert HPV assay in women starting antiretroviral treatment in South Africa.

International journal of STD & AIDS·2026
Same journal

Perceptions of acceptability and preferences surrounding a hypothetical syphilis vaccine in Lima, Peru.

International journal of STD & AIDS·2026
See all related articles

Related Experiment Video

Updated: Jun 2, 2026

A Rat Model of EcoHIV Brain Infection
08:48

A Rat Model of EcoHIV Brain Infection

Published on: January 21, 2021

Limbic encephalitis secondary to HIV seroconversion.

J Scriven1, S Davies, A K Banerjee

  • 1Department of Infection and Tropical Medicine, Birmingham Heartlands Hospital, Birmingham, UK. jescriven1@mac.com

International Journal of STD & AIDS
|April 26, 2011
PubMed
Summary
This summary is machine-generated.

Acute limbic encephalitis can occur during human immunodeficiency virus (HIV) seroconversion. Treatment with antiretroviral therapy, steroids, and immunoglobulin led to neurological recovery in this case.

More Related Videos

Identification of EcoHIV-Infected Cells in Microglia-Manipulated Transgenic Mice
07:23

Identification of EcoHIV-Infected Cells in Microglia-Manipulated Transgenic Mice

Published on: December 20, 2024

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Related Experiment Videos

Last Updated: Jun 2, 2026

A Rat Model of EcoHIV Brain Infection
08:48

A Rat Model of EcoHIV Brain Infection

Published on: January 21, 2021

Identification of EcoHIV-Infected Cells in Microglia-Manipulated Transgenic Mice
07:23

Identification of EcoHIV-Infected Cells in Microglia-Manipulated Transgenic Mice

Published on: December 20, 2024

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Area of Science:

  • Neurology
  • Infectious Diseases
  • Immunology

Background:

  • Human immunodeficiency virus (HIV) infection can manifest with diverse neurological complications.
  • Acute limbic encephalitis is a rare but serious neurological condition affecting the limbic system.

Observation:

  • A case of acute limbic encephalitis was observed in a patient during the seroconversion period of HIV.
  • The patient presented with neurological deficits indicative of limbic system involvement.

Findings:

  • The patient received a combination of antiretroviral therapy, corticosteroids, and intravenous immunoglobulin.
  • A gradual but significant neurological recovery was noted following the implemented treatment regimen.

Implications:

  • This case highlights the potential for HIV seroconversion to trigger autoimmune neurological conditions like limbic encephalitis.
  • Early diagnosis and comprehensive treatment, including antiretroviral therapy and immunomodulatory agents, are crucial for favorable outcomes in HIV-associated limbic encephalitis.