Related Experiment Video
Updated: Jun 2, 2026

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
Published on: February 27, 2019
Inhouse authorization center to improve reimbursement for outpatient chemotherapy infusions
1Clinical Authorization Center, Norris Cancer Hospital, University of Southern California, Los Angeles, CA 90033, USA. shetal.desai@usc.edu
Purpose:
The use of an inhouse authorization center to improve reimbursement for outpatient chemotherapy infusions is described.
Summary:
Investigation of current processes revealed deficiencies in the coordination of an insurance authorization process at Norris Cancer Hospital, as chemotherapy orders were not always reviewed for third-party payer authorization. Same-day chemotherapy treatment was often provided incident to a secondary oncology consultation, resulting in higher payer denials due to the absence of advanced authorization for treatment. The authorizations conducted by nonclinical hospital personnel were often incomplete and inconsistent with the policies and procedures established by third-party payers. Treatments for off-label indications were deemed experimental by the payers and required extensive documentation and review time by the payer in order to authorize treatment. These requirements were not consistently followed by the hospital facility, causing disruptions in the payment revenue cycle due to a high volume of claim disputes and, consequently, unpaid claims. A clinically staffed authorization department was created to obtain third-party payer authorizations and serve as a centralized clinical department within the hospital to interface with payers and manufacturer-sponsored patient assistance programs. Within the first year of the center's inception, over $500,000 in drug replacement was recovered through patient assistance programs and a total of $1.4 million was recovered within 2.5 years. The number of disputed claims was also reduced.
Conclusion:
Implementation of a clinical authorization process and use of manufacturer-driven patient assistance programs led to a reduction of disputed claims from third-party commercial payers and substantial savings in chemotherapy charges from January 2008 through July 2010.
Related Concept Videos
Health Information Technology and Healthcare Information System
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
Specialized Care Centers and Settings-II
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
Integrated Healthcare System
Specialized Care Centers and Settings-I
Daycare centers
They provide several functions. Some facilities care for healthy newborns and children whose parents work, while others are medically focused and care for...
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
