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Related Concept Videos

Blood Flow01:29

Blood Flow

Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Autoregulation of Blood Flow01:17

Autoregulation of Blood Flow

Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Structure of Blood Vessels01:15

Structure of Blood Vessels

Blood is circulated throughout the human body through a network of blood vessels called the circulatory system. This system includes arteries that transport blood from the heart to various body parts. These arterial pathways divide into smaller vessels until they reach the arterioles, which further split into capillaries. It is within these minuscule capillaries that the exchange of nutrients and waste products takes place. After this exchange, the blood is collected by venules, which fuse to...
Overview of the Cardiovascular System01:14

Overview of the Cardiovascular System

The cardiovascular system is a vital transportation system in the body. It comprises the heart and blood vessels and facilitates the exchange of gases, nutrients, and waste products.
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
Anatomy of Blood Vessels01:20

Anatomy of Blood Vessels

The vascular system, an integral part of the circulatory system, comprises various blood vessels that play crucial roles in maintaining the body's homeostasis. These blood vessels form a complex and efficient circulatory network. The three primary categories of blood vessels are the arteries, veins, and capillaries.
Arteries
Arteries circulate oxygenated blood from the heart, except the pulmonary artery, which transports deoxygenated blood to the lungs. Large arteries, such as the aorta, have...
Overview of Blood Vessels01:14

Overview of Blood Vessels

The human cardiovascular system comprises five primary types of blood vessels: arteries, arterioles, veins, venules, and capillaries, each serving unique functions.
Arteries and Arterioles: Arteries are muscular and elastic vessels that primarily carry oxygenated blood from the heart to body tissues, except for the pulmonary artery, which carries deoxygenated blood. They have thick walls to withstand high pressure and contain a layer of muscle tissue, allowing them to expand or contract as...

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[Pulmonary artery denervation in pulmonary hypertension: physiological and clinical aspects].

Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery·2021
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[Spontaneous fibrinolysis and possibilities of its acceleration in pulmonary embolism].

Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery·2021
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[Pulmonary hemodynamics following experimental myocardial ischemia after the blockade of adrenergic receptors].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova·2015
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[The role of the adreno-cholinergic interaction in the pulmonary hemodynamics changes following myocardial ischemia].

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[Hemodynamic mechanisms of the superior and inferior vena cava flow changes following experimental myocardial ischemia].

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[The pulmonary hemodynamics changes following experimental myocardial ischemia in rabbits with decreased arterial pressure].

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Related Experiment Video

Updated: Jun 2, 2026

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
07:30

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling

Published on: November 3, 2015

[Organ vessel functions by pulsatile flow].

I Z Poiasov

    Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova
    |April 27, 2011
    PubMed
    Summary

    Skeletal muscle hemodynamics, including resistance and capacity, are influenced by blood flow's amplitude and frequency. These relationships are nonlinear, with pulsatile flow oscillations significantly impacting exchange vessel function.

    Area of Science:

    • Physiology
    • Biophysics

    Context:

    • Skeletal muscle perfusion is crucial for nutrient and waste exchange.
    • Understanding hemodynamic regulation is key to physiological function.

    Purpose:

    • To investigate the relationship between pulsatile blood flow characteristics and skeletal muscle hemodynamics.
    • To determine the nonlinear amplitude-frequency dependencies of hemodynamic parameters.

    Summary:

    • Skeletal muscle resistance, capacity, and exchange vessel functions depend nonlinearly on blood flow amplitude and frequency.
    • Perfusion conditions (constant flow vs. constant pressure) alter hemodynamic responses to pulsatile flow modulation.
    • Pulsatile blood flow oscillations have the greatest impact on exchange vessel function.

    Impact:

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    • Identified critical ranges of blood flow amplitude and frequency affecting skeletal muscle hemodynamics.
    • Proposed a novel 'wave regulation' conception for organ vessel function.
    • Provides insights into the complex interplay between blood flow dynamics and microvascular regulation.