Recent patents on the baculovirus systems

Area of Science:

• Biotechnology
• Molecular Biology
• Gene Therapy

Background:

• Baculovirus has been a key tool for protein production in insect cells for approximately 30 years.
• In the last decade, baculovirus has gained attention as a gene delivery vector for mammalian cells and animals.

Purpose of the Study:

• To review significant patents related to baculovirus applications.
• To focus on vector development, novel applications, and downstream processing of baculovirus systems.

Main Methods:

• Patent literature review.
• Analysis of patents concerning baculovirus for insect cell infection.
• Examination of patents on baculovirus for mammalian cell transduction.

Main Results:

• Identification of key patents in baculovirus vector development.
• Summary of emerging applications of baculovirus in gene delivery.
• Overview of patented downstream processing techniques.

Conclusions:

• Baculovirus technology is evolving with significant patent activity in both established and new application areas.
• Patents reflect advancements in baculovirus vector design and its expanding role in gene therapy and bioproduction.