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Comparison of two different speckle tracking software systems: does the method matter?

Patric Biaggi1, Shemy Carasso, Patrick Garceau

  • 1Division of Cardiology, Peter Munk Cardiac Program, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada. pbiaggi@gmx.ch

Echocardiography (Mount Kisco, N.Y.)
|April 27, 2011
PubMed
Summary
This summary is machine-generated.

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Echocardiographic speckle tracking strain measurements vary between software. Time to peak strain and strain gradients are comparable, but peak strain values differ, requiring careful clinical consideration.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Echocardiographic speckle tracking strain analysis is increasingly important in clinical practice.
  • Comparability of strain measurements across different software platforms remains poorly defined.

Purpose of the Study:

  • To compare left ventricular (LV) two-dimensional (2D) peak strain and time to peak strain (TTP) between EchoPAC (2DS) and velocity vector imaging (VVI) software.
  • To assess the agreement of global, anatomical, and segmental strain values and TTP between the two systems.

Main Methods:

  • 47 healthy subjects underwent echocardiography.
  • LV longitudinal (LS), circumferential (CS), and radial strain (RS) peak values and TTP were analyzed using EchoPAC (2DS) and VVI.
  • Global, anatomical level, and segmental values were compared using Pearson correlation and significance testing.

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Main Results:

  • Global peak strain correlations (r) between 2DS and VVI were 0.68 (LS), 0.44 (CS), and 0.59 (RS).
  • Global TTP correlations were higher: 0.81 (LS), 0.80 (CS), and 0.68 (RS).
  • Significant differences in segmental peak strain were found in most segments for CS and RS, while segmental TTP differences were less frequent.

Conclusions:

  • Time to peak strain (TTP) and strain gradients show good comparability between VVI and 2DS software.
  • Most peak strain values are not comparable between the two software systems.
  • Software dependency of peak strain necessitates caution in clinical applications; further studies on diagnostic accuracy are needed.