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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...

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Related Experiment Video

Updated: Jun 2, 2026

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
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A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

Published on: February 1, 2016

Vascular imaging with positron emission tomography.

F Joshi1, D Rosenbaum, S Bordes

  • 1Division of Cardiovascular Medicine, University of Cambridge, Cambridge, UK.

Journal of Internal Medicine
|April 27, 2011
PubMed
Summary

Positron emission tomography (PET) imaging with fluorodeoxyglucose (FDG) can measure arterial inflammation, a key factor in atherosclerosis. This technique may help assess novel anti-atherosclerotic drugs and predict cardiovascular events.

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Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG
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Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

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Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
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Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules

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Last Updated: Jun 2, 2026

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
14:19

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Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG
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Non-invasive Imaging and Analysis of Cerebral Ischemia in Living Rats Using Positron Emission Tomography with 18F-FDG

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Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
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Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules

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Area of Science:

  • Cardiovascular Imaging
  • Inflammatory Disease Research
  • Nuclear Medicine

Background:

  • Atherosclerosis is a major cause of cardiovascular events like heart attacks and strokes.
  • Current diagnostic methods like angiography primarily assess luminal narrowing, not vessel wall inflammation.
  • Despite therapies, atherosclerosis remains a significant global health issue.

Purpose of the Study:

  • To review the evidence, limitations, and applications of fluorodeoxyglucose-positron emission tomography (FDG-PET) in vascular imaging.
  • To explore FDG-PET's potential for assessing arterial inflammation and guiding anti-atherosclerotic drug development.
  • To discuss alternative PET tracers and imaging modalities for vascular inflammation.

Main Methods:

  • Review of existing literature on FDG-PET for imaging arterial inflammation.
  • Analysis of FDG uptake in relation to macrophage activity and glucose metabolism in atherosclerotic plaques.
  • Comparison of FDG-PET with conventional imaging techniques and other emerging modalities.

Main Results:

  • FDG-PET highlights areas of high glucose metabolism in atherosclerotic plaques, indicative of macrophage activity.
  • FDG accumulation in the vessel wall correlates with inflammation levels and cardiovascular risk factors.
  • FDG-PET shows promise for early efficacy assessment of novel anti-atherosclerotic therapies.

Conclusions:

  • FDG-PET is a valuable tool for non-invasively assessing vascular inflammation in atherosclerosis.
  • This imaging modality may aid in predicting cardiovascular events and monitoring treatment response.
  • Further research into FDG-PET and alternative tracers is crucial for advancing vascular imaging.