Factor VII deficiency first observed at preoperative routine clotting test

Area of Science:

• Hematology
• Coagulation Disorders
• Dental Surgery

Background:

• Factor VII deficiency is a rare inherited bleeding disorder.
• Optimal Factor VII levels for surgical procedures, particularly dental extractions, are not well-established.

Observation:

• A 24-year-old female with a Factor VII level of 22% (mildly deficient) was evaluated prior to an impacted tooth extraction.
• Replacement therapy with Factor IX complex was not administered preoperatively.

Findings:

• The patient underwent tooth extraction without any signs of abnormal postoperative bleeding.
• This case suggests that individuals with mild Factor VII deficiency may tolerate dental extractions without specific hemostatic support.

Implications:

• The findings contribute to understanding the minimum safe Factor VII levels for dental procedures.
• This case provides valuable clinical data for managing patients with rare Factor VII deficiency undergoing oral surgery.