Related Experiment Video
Updated: Jun 2, 2026

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
Published on: June 6, 2025
[Roles of signal transduction pathway in non-Hodgkin's lymphoma]
1Department of Hematology, Shandong University, Jinan 250021, Sandong Province, China.
Abstract:
The study of signal pathway has become a hotspot and a key in life science. In recent years, it has been found that many signaling pathways are associated with the occurrence, development, prognosis and drug resistance of many malignancies, including non-Hodgkin's lymphoma (NHL). Understanding the biological function of the signaling pathway and its relation with NHL, selectively controlling its biological activities may provide a new way for the treatment of NHL. In order to further investigate the function of signal pathways in pathogenesis, development and treatment of NHL, this review summarizes briefly the advances in the signal pathways related with the NHL including NF-κB, PI3K-AKT, Notch, Hh, MAPK, JAK-STAT, Wnt and cAMP.
Related Concept Videos
Signal Transduction: Overview
Typically, signal transduction involves three...
Interactions Between Signaling Pathways
Convergence and divergence, and cross-talk between signaling pathways
Two distinct signaling pathways can converge on a single functional unit, which may either be a single protein or a complex of proteins. The response is either functionally distinct or synergistic between the two pathways but different from the response...
Non-Canonical Wnt Signaling Pathways
Non-Canonical Wnt Signaling Pathways
The JAK-STAT Signaling Pathway
Amplifying Signals via Enzymatic Cascade

