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Updated: Jun 2, 2026

Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging

Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging

Published on: April 14, 2011

Tumoral calcinosis: a case report.

Yuen Yee Leung¹, Raymond Lai

¹Department of Orthopaedics and Traumatology, United Christian Hospital, Hong Kong. verityhaze@gmail.com

Journal of Orthopaedic Surgery (Hong Kong)

|April 27, 2011

Summary

This case study details a rare instance of tumoral calcinosis in an 11-year-old girl presenting as elbow swelling. Surgical excision confirmed the benign nature of the calcified mass, with no recurrence after four years.

Area of Science:

Orthopedics
Radiology
Pathology

Background:

Tumoral calcinosis is a rare metabolic disorder characterized by calcium salt deposition in soft tissues, often around joints.
This condition can mimic other bone and soft tissue pathologies, necessitating accurate diagnostic approaches.

Observation:

An 11-year-old girl presented with progressive right elbow swelling following a contusion.
Imaging revealed a densely calcified lesion without fracture or periosteal reaction; bone scan showed increased uptake in the elbow, buttock, and acetabulum.
A large, lobulated yellowish mass with chalky material was surgically excised, measuring 9x7x4 cm.

Findings:

Histological examination confirmed tumoral calcinosis, characterized by fibrous septa, fibroblastic proliferation, foreign body giant cells, and histiocytic cells.

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No evidence of malignancy was found in the excised mass.

Subsequent excision of lesions in the left elbow and buttock also confirmed tumoral calcinosis.

Implications:

This case highlights the importance of considering tumoral calcinosis in the differential diagnosis of pediatric soft tissue masses, especially those with calcification.
Surgical excision appears to be an effective treatment for symptomatic tumoral calcinosis, with a favorable long-term prognosis.
Further research into the underlying mechanisms and genetic factors of tumoral calcinosis may improve diagnostic and therapeutic strategies.