Calcinosis cutis of the hand in a renal failure patient: a case report

A 25-year-old woman with end-stage renal failure presented with subcutaneous calcinosis cutis that grew rapidly in both hands. Radiographs showed subcutaneous lobulated calcific deposits. Magnetic resonance imaging revealed a heterogeneous mass encasing segments of the abductor pollicis longus and extensor pollicis brevis tendons. Excision of the masses was performed. Histopathology revealed amorphous calcified deposits in fibrous tissue and a foreign body reaction. There was no evidence of a tubercular lesion. Further investigation revealed the presence of hyperphosphataemia and secondary hyperparathyroidism, despite a normal serum calcium level. Oral phosphate-lowering agents failed to control the condition, and recurrence was noted 6 months later. The patient finally underwent parathyroidectomy and has had no further recurrence.