Related Experiment Video
Updated: Jun 2, 2026

Three-dimensional Quantification of Intestinal Mucus Using Whole-mount Tissue Imaging
Published on: September 12, 2025
[A case of Menetrier's disease showing mucus bridge observed during endoscopy]
Jong Min Hwang1, Gwang Ha Kim, Won Jin Kim
1Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Abstract:
Menetrier's disease is a rare entity characterized by large, tortuous gastric mucosal folds. The mucosal folds in Menetrier's disease are often most prominent in the body and fundus. Histologically, massive foveolar hyperplasia (hyperplasia of surface and glandular mucous cells) is noted, which replaces most of the chief and parietal cells. Profuse mucus is usually observed during the endoscopy but there have been few cases that show interesting endoscopic findings such as mucus bridge or water pearl. Herein, we report a case of Menetrier's disease showing mucus bridge by excessive mucus observed during the endoscopy.
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