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Updated: Jun 2, 2026

In Vesiculo Synthesis of Peptide Membrane Precursors for Autonomous Vesicle Growth
Published on: June 28, 2019
Fluorescent vesicles consisting of galactose-based amphiphilic copolymers with a π-conjugated sequence self-assembled
Karim Aissou1, André Pfaff, Cristiano Giacomelli
1Centre de Recherches sur les Macromolécules Végétales (CERMAV, CNRS-UPR 5301), BP 53, 38041 Grenoble Cedex 9, France.
Abstract:
Fluorescent vesicles considered as a mimic of natural primitive cells are prepared from poly(3-hexylthiophene)-block-poly(3-O-methacryloyl-D-galactopyranose) P3HT-b-PMAGP copolymers. The unique characteristic of such vesicular nanostructures is their architecture, which comprises a hydrophobic π-conjugated P3HT wall stabilized by a hydrophilic PMAGP interface featuring glucose units. The results of this work offer a very efficient and straightforward method for engineering well-controlled fluorescent nanoparticles (without the addition of dyes), which provide an excellent support to the study of carbohydrate-protein interactions.
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