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Related Concept Videos

Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

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Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
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[Intestinal invagination: change in its incidence from 1987 to 2008].

X Bringué Espuny1, Z Ibars Valverde, M Martínez Alonso

  • 1Hospital Universitari Arnau de Vilanova, Lleida. xbringue@comll.cat

Cirugia Pediatrica : Organo Oficial De La Sociedad Espanola De Cirugia Pediatrica
|April 28, 2011
PubMed
Summary

Intestinal invagination incidence has significantly decreased in children under three over 21 years. This epidemiological trend is crucial for understanding the impact of rotavirus vaccines on intussusception rates.

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Published on: October 22, 2013

Area of Science:

  • Pediatric epidemiology
  • Gastroenterology
  • Vaccinology

Context:

  • Intestinal invagination (intussusception) is a significant cause of bowel obstruction in infants and young children.
  • Recent introduction of rotavirus vaccines necessitates updated local epidemiological data on intussusception incidence.
  • Previous studies suggest a declining trend in intussusception rates.

Purpose:

  • To ascertain the long-term trend and current incidence of intussusception in a specific geographic area.
  • To analyze epidemiological data over a 21-year period.
  • To provide reliable local data relevant to rotavirus vaccine impact.

Summary:

  • A retrospective review of intussusception cases in patients under 3 years old was conducted over 21 years.
  • Results indicate a statistically significant decrease in intussusception incidence.
  • Incidence dropped from 17.74/10,000 girls and 30.04/10,000 boys in 1987 to 0.27/10,000 girls and 0.49/10,000 boys in 2008.

Impact:

  • Demonstrates a substantial decline in intussusception, particularly in infants under one year.
  • Highlights the importance of ongoing epidemiological surveillance for vaccine impact assessment.
  • Provides critical data for public health strategies and resource allocation in pediatric care.