Related Experiment Video
Updated: Jun 2, 2026

08:01
Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
Published on: April 21, 2022
Localized malignant lymphohistiocytoid pleural mesothelioma
A Ouazzani1, B Rondelet, Y Sokolow
1Department of Thoracic Surgery, Erasme University Hospital, Brussels, Belgium.
Acta Chirurgica Belgica
|April 28, 2011
Summary
This case study details a rare, localized malignant lymphohistiocytoid mesothelioma in a 42-year-old man. The patient achieved long-term survival without recurrence after surgical resection, highlighting a unique outcome for this rare pleural neoplasm.
Area of Science:
- Oncology
- Thoracic Surgery
- Pathology
Background:
- Pleural mesothelioma is a rare malignancy with limited treatment options.
- Malignant lymphohistiocytoid mesothelioma is an exceptionally rare histological subtype.
- Localized presentations of pleural mesothelioma are uncommon.
Observation:
- A 42-year-old male presented with a right pleural mesothelioma.
- The neoplasm was localized, identified via imaging and thoracoscopy, and confirmed pathologically.
- The patient underwent a curative pleuro-pneumonectomy.
Findings:
- The histological subtype was identified as malignant lymphohistiocytoid mesothelioma, a rare variant.
- Postoperatively, the patient remains alive and recurrence-free at 6 years and 5 months.
- This long-term survival contrasts with previously reported cases with recurrence.
Implications:
- This case expands the understanding of malignant lymphohistiocytoid mesothelioma outcomes.
- Successful surgical management of localized forms can lead to prolonged survival.
- Further research into rare mesothelioma subtypes and long-term prognoses is warranted.
More Related Videos
Related Concept Videos
Pleural Disorders: Types and Brief Description
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
Pleura of the Lungs
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
Pleural Effusion II: Symptoms and Management
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Pleural Effusion I: Introduction
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
Pulmonary Tuberculosis III
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:

