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Diabetic non-ketotic hyperglycaemia presenting as chorea--a case report
The Medical Journal of Malaysia
|September 1, 1990
Summary
Hyperosmolar non-ketotic hyperglycemia can cause chorea, a movement disorder. This symptom resolved with metabolic correction but recurred with worsening sepsis, suggesting a link to cerebral ischemia.
Area of Science:
- Neurology
- Endocrinology
- Infectious Diseases
Background:
- Hyperosmolar non-ketotic hyperglycemia is a serious diabetic complication.
- Chorea is an abnormal involuntary movement disorder.
Observation:
- A patient presented with hyperosmolar non-ketotic hyperglycemia, chorea, and septic arthritis.
- The chorea resolved upon correction of hyperglycemia.
Findings:
- Chorea recurred with the patient's worsening septicemia and metabolic decompensation.
- This suggests a potential link between non-ketotic hyperglycemia, sepsis, and neurological dysfunction, possibly involving cerebral ischemia.
Implications:
- Highlights the potential for neurological manifestations in metabolic disturbances.
- Suggests that prompt management of hyperglycemia and sepsis is crucial for resolving neurological symptoms.
- Further research is needed to elucidate the exact mechanisms of focal neurological signs in non-ketotic hyperglycemia.