Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genomic Diversity of Aurochs From a Mediterranean Ice-Age Refugium.

Molecular ecology·2026
Same author

Individual Comparative PK Evaluation of Single-dose Octocog Alfa, Rurioctocog Alfa Pegol, and Efanesoctocog Alfa in Adults with Severe Hemophilia A.

TH open : companion journal to thrombosis and haemostasis·2026
Same author

Lethal plague outbreaks in Lake Baikal hunter-gatherers 5,500 years ago.

Nature·2026
Same author

Characteristics and Occupational Trends of Military Tactical Athletes with Repeat Atrial Fibrillation Catheter Ablations.

Military medicine·2026
Same author

Reddit and rare diseases: what myositis communities tell us about support and struggle.

Oxford open digital health·2026
Same author

Population discontinuity in the Paris Basin linked to evidence of the Neolithic decline.

Nature ecology & evolution·2026
Same journal

Commentary on: Maskell PD, de Korompay A. Letter to the Editor-The transition point from zero-order to first order in blood alcohol elimination curves. Where is it? J Forensic Sci. 2025;70 (1):398-400. https://doi.org/10.1111/1556-4029.15650.

Journal of forensic sciences·2026
Same journal

A novel relationship between time offsets in capillary electrophoresis and DNA sequence variations in short tandem repeats.

Journal of forensic sciences·2026
Same journal

A 4-zone model to determine fentanyl overdose probability.

Journal of forensic sciences·2026
Same journal

Authors' response.

Journal of forensic sciences·2026
Same journal

Determining the utility of radio frequency identification (RFID) technology for disaster victim identification (DVI).

Journal of forensic sciences·2026
Same journal

Stakeholders' perspectives on integrating point-of-care diagnostics into forensic death investigations in South Africa.

Journal of forensic sciences·2026
See all related articles

Related Experiment Video

Updated: Jun 2, 2026

Obtaining High Quality RNA from Single Cell Populations in Human Postmortem Brain Tissue
18:17

Obtaining High Quality RNA from Single Cell Populations in Human Postmortem Brain Tissue

Published on: August 6, 2009

Bone marrow and bone as a source for postmortem RNA.

Nienke L van Doorn1, Andrew S Wilson, Eske Willerslev

  • 1Department of Archaeological Science, University of Bradford, Richmond Road, BD1 5DD Bradford, UK.

Journal of Forensic Sciences
|April 28, 2011
PubMed
Summary
This summary is machine-generated.

Bone marrow RNA offers a promising method for estimating time since death in forensic investigations. This study found RNA in bone marrow for up to 21 days postmortem, suggesting its utility.

More Related Videos

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
07:17

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

Published on: April 14, 2016

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
12:53

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species

Published on: May 19, 2018

Related Experiment Videos

Last Updated: Jun 2, 2026

Obtaining High Quality RNA from Single Cell Populations in Human Postmortem Brain Tissue
18:17

Obtaining High Quality RNA from Single Cell Populations in Human Postmortem Brain Tissue

Published on: August 6, 2009

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
07:17

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

Published on: April 14, 2016

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
12:53

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species

Published on: May 19, 2018

Area of Science:

  • Forensic Science
  • Molecular Biology
  • Biochemistry

Background:

  • RNA degradation is a factor in estimating time since death.
  • Tissue type significantly influences RNA stability for forensic analysis.

Purpose of the Study:

  • To evaluate bone marrow as a source for postmortem RNA.
  • To determine the stability of RNA in bone marrow over time after death.

Main Methods:

  • RNA extraction from rabbit bone and bone marrow postmortem.
  • Quantification of three RNA transcripts using real-time polymerase chain reaction.
  • Assessment of RNA integrity using Bioanalyzer.

Main Results:

  • Total RNA was successfully extracted from bone marrow samples.
  • Detectable levels of specific RNA transcripts were quantified.
  • Ribosomal RNA (rRNA) bands were observed in bone marrow up to 21 days postmortem.

Conclusions:

  • Bone marrow is a viable source for postmortem RNA analysis.
  • RNA from bone marrow can be detected for an extended period after death.
  • This finding supports the use of bone marrow for time-since-death estimations in forensic science.