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Updated: Jun 2, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
1-Benzoyl-3-ethyl-3-phenyl-thio-urea
Aisha A Al-Abbasi1, Mohammad B Kassim
1School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi Selangor, Malaysia.
Abstract:
In the title compound, C(16)H(16)N(2)OS, the conformation at the two partially double C-N bonds of the thio-urea unit is E. The amide group is twisted relative to the thio-urea fragment, forming a dihedral angle of 62.44 (16)°, and the two phenyl rings form a dihedral angle 75.93 (18)°. In the crystal, mol-ecules are linked by N-H⋯S hydrogen bonds, forming centrosymmetric dimers.
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